What is the use of cellulose acetate phthalate?
Cellulose acetate phthalate (CAP), a pharmaceutical excipient used for enteric film coating of capsules and tablets, was shown to inhibit infection by the human immunodeficiency virus type 1 (HIV-1) and several herpesviruses.
What is cellulose acetate?
Cellulose acetate is an insoluble cellulose derivative regarded as a nontoxic, nonirritant, and biodegradable material. It is heat-resistant and less hygroscopic. Cellulose acetate is partially acetylated cellulose, in which the acetyl content ranges from 29.0% to 44.8%, corresponding to mono-, di-, and triacetate.
Is cellulose acetate phthalate biodegradable?
Cellulose acetate phthalate (CAP) is a crystalline, hydrophilic and inherently biodegradable polymer that has widespread use in pharmaceuticals as a coating on tablets [[53], [54], [55]].
What is CAP polymer?
Cellulose acetate phthalate (CAP), also known as cellacefate (INN) and cellulosi acetas phthalas, is a commonly used polymer phthalate in the formulation of pharmaceuticals, such as the enteric coating of tablets or capsules and for controlled release formulations.
What is used for enteric coating?
Materials used for enteric coatings include fatty acids, waxes, shellac, plastics, and plant fibers. Conventional materials used are solutions of film resins.
What is the monomer of cellulose acetate?
It is made up of repeating glucose units that have the chemical formula C6H7O2 (OH)3 and the following molecular structure: The deficiencies inherent in cellulose nitrate raised the possibility of producing other esters of cellulose,…
Is cellulose and cellulose acetate the same?
While cellulose and cellulose acetate are technically thermoplastic polymers, the tight ordering of cellulose means it is insoluble in organic solvents and doesn’t flow with heat. On the other hand, cellulose acetate (CA) tends to be soluble in certain organic solvents and can flow with heat.
Is cellulose acetate eco-friendly?
Cellulose acetate is an eco-friendly material made from cellulose obtained from wood produced in sustainably managed forests or cotton linters (the hairy fibers that cling to cotton seeds after harvesting) combined with acetic acid, the main constituent of vinegar.
Is cellulose acetate toxic?
There is no evidence of any toxic effects of cellulose acetate phthalate under these conditions.
What is SP capacitor?
“SP-Cap” is a rectangular chip-shaped aluminum electrolytic capacitor that uses a polymer as its electrolyte. SP-Cap has several features including low ESR, low ESL, long life span, small size, low profile, and high characteristic stability.
Is Cap soluble in water?
CAP has been used for enteric film coating of tablets and capsules [15] and thus has a well-established safety record for human use. CAP is not soluble in water at pH <≈5.8. For this reason, it must be used in a micronized form for both tablet coating from water dispersions, and as a topical microbicide.
Which polymers are used in enteric coating of tablets?
Methacrylic acid methylmethacrylate copolymers (Eudragit L and S), and methacrylic acid ethyl acrylate copolymer (Eudragit L30D) are the preferred choice of coating polymers for enteric formulations. They allow targeting of specific areas of the intestine.
Which type of polymer is cellulose acetate?
semi-synthetic polymer
Cellulose acetate (rayon) is a semi-synthetic polymer.
What is the difference between acetate and cellulose acetate?
Acetate or cellulose acetate is a type of cellulose that contains two acetate groups bound to a glucose molecule. It can refer to any acetate ester of cellulose, but specifically to cellulose diacetate. This substance has applications in film base in photography and as a component in some coatings.
How do you identify cellulose acetate?
Deterioration of cellulose acetate can be detected and measured using the Acid Detection (AD) strip test, which requires 24–48 h to collect a measurement. The AD strips, developed specifically for cellulose acetate films, are acid–base indictor paper strips that change colour in the presence of acidic vapour.